X.org mouse click/focus woes

[Tyler Aviss]

I'm having issues in X where I can move the cursor with my mouse, click
buttons with the keyboard, but not click/focus with the most.

It happens in both gnome and KDE, with various mice (mouse?). I tried a
fresh reinstall to fix it but it's still occurring, even after going from
Ubuntu 10 to 12.

It *does* seen to go away if I logout + logon, but returns after the next
reboot.

Google hasn't provided any useful hints yet.

This is on a Zotac Ion box /w nforce chipset.

Ideas?
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